Which of the following factors can contribute to leakage in an ionization chamber measuring system?

The factors contributing to leakage in an ionization chamber measuring system primarily relate to the components and connections within the system. The chamber itself must maintain its integrity, as any physical defects can allow for unintended interaction with the surrounding environment, leading to measurement inaccuracies. Additionally, the electrometer, responsible for measuring the ionization current, needs to be functioning correctly; any malfunction or poor calibration could introduce errors. The connecting cable plays a crucial role, as any damage or incorrect shielding can lead to signal loss or interference, causing leakage in the measurements.

In essence, the specific components of the system, such as the chamber, electrometer, and cables, are critical in ensuring accurate readings and preventing leakage, making this option the most relevant.